L Transurethral resection of the prostate
Transurethral resection of the prostate (TURP) is one of the most commonly performed surgical procedures in men older than 60 years of age. These patients are often at greater anesthetic risk because they are more likely to have cardiovascular or pulmonary problems. The procedure consists of opening the outlet channel from the bladder with the use of a resectoscope in the urethra for electrically cutting away the obstructing median and lateral lobes of prostate tissue. Bleeding is controlled with a coagulation current. For visualization of the surgical field continuous irrigation is used to wash away blood and dissected prostatic tissue and to distend the bladder.
Various types of irrigating fluid have been used. Although distilled water is associated with the least optical impairment, hemolysis of red blood cells is an unacceptable side effect. Normal saline or lactated Ringer solution is highly ionized and promotes dispersion of high current from the resectoscope. For these reasons, irrigating solutions typically consist of sorbitol (2.70 g) and mannitol (0.54 g) in 100 mL of water (Cytal) or glycine 1.5%. Glycine is slightly hypoosmolar to the blood but is used widely because of its low cost. Average features of a TURP are listed in the following table.
Average Parameters with a TURP
Parameter | Average |
Resection time | <77 min |
Resectate mass | 20-48 g |
Absorbed volume | 1 L |
Blood loss | 175-534 mL |
Speed of TURP syndrome onset | 15 min |
Serum sodium nadir | 132-135 mmol/L |
Adapted from Gravenstein D, Hahn RG. TURP syndrome. In Lobato EB, Gravenstein N, Kirby, RR, et al, eds. Complications of Anesthesiology. Philadelphia: Lippincott Williams & Wilkins; 2008: 474-491.
Key Points for Anesthesia Management of Transurethral Resection of the Prostate