Proximal Humerus Fracture: Open Reduction, Internal Fixation—Locking Plate
Andrew Choo
Carolyn Meinerz
INDICATIONS
Proximal humerus fractures remain a common orthopaedic injury and are frequently associated with osteopenia and osteoporosis.1 However, as with many skeletal injuries, there is a bimodal distribution of fractures, with low-energy fragility fractures common in elderly patients and higher-energy injuries occurring in a younger patient population. It should be emphasized that the majority of proximal humerus fractures can and should be treated nonoperatively, but there remains a place for operative management of these injuries, specifically with open reduction and internal fixation (ORIF).
Absolute indications for surgery for proximal humerus fractures include fracture-dislocations, open fractures, and patients with vascular compromise. Fortunately, these indications remain quite rare and the majority of surgical indications remain relative. These are typically related to the amount of displacement of various fracture components as well as the age, activity, and expectations of the patient. Significant controversy exists regarding the operative treatment of proximal humerus fractures, and multiple prospective randomized controlled trials have not demonstrated a clear benefit.2, 3, 4 and 5
The largest of these was the PROFHER trial, which randomized more than 230 patients with displaced proximal humerus fractures into nonoperative versus operative management. No significant differences between the groups were found in Oxford Shoulder Scores, SF-12 scores, complications, or mortality at 2-year follow-up, and these results held at 5-year follow-up.6,7 Despite this being the best-quality evidence to date, surgery continues to be performed for proximal humerus fractures with many factors cited as support. First, most of the studies that have examined these fractures have been skewed or have specificallylooked at the elder patient population. In the PROFHER trial, the average age was 66 years, thus potentially diminishing its generalizability to a younger patient cohort. As mentioned, younger patients often have higher-energy mechanisms with potentially more displacement, associated soft-tissue injury, and instability. In addition, younger and more functionally demanding patients may require a closer restoration of normal anatomy to have a satisfactory result. Second, most of the past studies up until recently have not graded the quality of reduction specifically with ORIF when comparing outcomes in proximal humerus fractures. A recent study did find a benefit to a more anatomic reconstruction, which makes intuitive sense and suggests a possible contributing factor to the lack of benefit seen in some of the literature.8
Finally, another recent study highlights the variability in results with nonoperative treatment, clearly showing that not everyone will have a satisfactory outcome. Many factors beyond just fracture characteristics contributed to poor outcomes, but radiographic varus alignment, anterior translation of the humeral shaft, and tuberosity involvement in particular seemed to be associated with nonunion and poorer results.9 Again, these data speak of an intuition that greater displacement of a fracture will likely lead to poorer results if left untreated, though much work remains to be done to elucidate what factors matter the most for which patients.
If surgery has been selected, the next difficult decision to make is what type of surgery to perform for a particular proximal humerus fracture. In younger patients, efforts should typically be made at a joint preserving operation, such as ORIF. In older patients, the two main considerations should be the ability to obtain and maintain the reduction of the fracture as well as the risk of avascular necrosis (AVN). The bone quality, the amount of subchondral bone beneath the articular surface, and the number and size of the fracture fragments play strongly into this decision. There are data to suggest more highly comminuted/complex fractures in elderly patients benefit from reverse shoulder arthroplasty over ORIF.10 Algorithms have been designed to assist in this decision-making process, but the type of surgery chosen is also likely influenced by the surgeon’s comfort level and experience.11
Ultimately, the determination of nonoperative versus operative treatment and what type of operative treatment (if chosen) should be a shared decision-making model that involves thorough informed consent and buy-in from the patient. Transparent discussion regarding risks and benefits as well as expected functional outcomes allows patients to make appropriately informed decisions and sets expectations for recovery.
CONTRAINDICATIONS
Absolute contraindications include any active infection or inability to comply with postoperative restrictions. Relative contraindications include limited benefit to operative intervention such as if the patient is low demand and the risks outweigh the benefits. Additionally, poorer bone quality may be a relative contraindication to ORIF and potentially even arthroplasty. Those fracture patterns at particularly high risk of AVN (eg, a four-part fracture dislocation with no soft-tissue attachment to the humeral head) should be considered for arthroplasty rather than ORIF.
PREOPERATIVE EVALUATION
A detailed history is critical for informed decision making regarding operative or nonoperative management of proximal humerus fractures. A general history should include the knowledge of overall health, age, activity level, and mechanism of injury. Additionally, specific to the upper extremity is it is important to know hand dominance, level of independence, and occupation and/or hobbies.
Physical examination should include full exposure of the shoulder girdle and upper extremity. Evaluation of the skin and soft-tissues is important to assess for swelling, ecchymosis, or deformity. Deformity may represent fracture displacement or dislocation of the glenohumeral joint. Careful inspection of the injured and contralateral extremity may detect subtle differences in contours of the shoulder girdle and overlying soft-tissue envelope. Concomitant assessment of the cervical spine, clavicle, scapula, and acromion as well as chest wall are important for assessing other sources of pain and disability. Neurologic examination must include assessment of proximal musculature including the trapezius, rotator cuff muscles, deltoid, biceps, and triceps. Additionally, motor and sensory functions of the axillary, radial, median, and ulnar nerves should be assessed. The most commonly injured peripheral nerve in proximal humerus fractures, the axillary nerve, must be assessed.12 Sensation over the lateral aspect of the upper arm is not a reliable test for determining axillary nerve function. Formal motor examination of the axillary nerve (deltoid and teres minor) in the setting of a proximal humerus fracture is also challenging due to discomfort and positioning of the limb. Isometric deltoid contraction serves as an assessment for the overall integrity of the axillary nerve.
Complete imaging is paramount to making informed treatment decisions. Initial radiographs should include a true AP or Grashey, scapular Y, and axillary views. Plain radiographs provide details on the bone quality, amount of fracture displacement, glenohumeral dislocation, and overall alignment of the limb. Fracture characteristics include number of fragments, displacement, dislocation, presence of head split, and overall bone quality. The Neer classification was created to identify predictable fracture fragments.13 The four segments were defined as the greater tuberosity, lesser
tuberosity, articular humeral head, and humeral shaft. In clinical practice, the Neer classification is often used for communication, to guide treatment, and predict outcomes, though its true reliability is still in question.
tuberosity, articular humeral head, and humeral shaft. In clinical practice, the Neer classification is often used for communication, to guide treatment, and predict outcomes, though its true reliability is still in question.
Computed tomography (CT) has become a standard of care for diagnosis and treatment of proximal humerus fractures. These images provide additional information about intra-articular fracture lines, amount of bone available in the head for fixation, and quality and integrity of rotator cuff musculature. Addition of 3D reconstructions provides surgeons with additional detail and visualization for preoperative planning (Figure 29-1).
TECHNIQUE
Positioning
The foundation to a successful operation begins with appropriate patient positioning. The most commonly used positions for ORIF of proximal humerus fractures are beach chair and supine. Many factors contribute to the decision to use one versus the other, including surgeon familiarity, OR resources, concomitant injuries, ease of fluoroscopic imaging, anesthetic concerns, as well as the consideration for potential arthroplasty. Beach-chair positioning is often utilized by shoulder surgeons who routinely use this for elective shoulder procedures (Figure 29-2). The benefit of this position aside from familiarity is access to the entire shoulder if adjunctive or percutaneous incisions are needed as well as the ability to extend the shoulder in cases of arthroplasty or visualization of head-split fractures. Downsides of beach-chair positioning are the concerns for cerebral hypotension with the head of the patient elevated, as well as potential difficulties in the polytraumatized patient.
Intraoperative Fluoroscopy
Another important consideration related to the patient position is the ability to obtain appropriate fluoroscopic imaging. The C-arm can be brought in from the head of the patient or from the contralateral side, depending on the type of bed, position, and image intensifier used (Figure 29-3). Regardless, as with a patient with any fracture undergoing surgery, orthogonal views are required to judge appropriate reduction and safe fixation (Figure 29-4). An AP/PA view of the proximal humerus is the primary standard view obtained most frequently during ORIF. Although a Grashey view (true AP in the plane of the scapula separating the humeral head and the glenoid) is not necessary, a true AP of the proximal humerus should be used to judge the coronal plane reduction. In a true AP of the proximal humerus, there will be maximum separation between the profile of the greater tuberosity and the articular margin of the humeral head (Figure 29-5). When getting this image, it is important to consider the retroversion of the proximal humerus relative to the distal humerus/forearm, as well as ensure that the humeral diaphysis is parallel to the receiver of the image intensifier in order to avoid flexed or extended images.
![]() FIGURE 29-4 Grashey and axillary fluoroscopic views from the patient in Figure 29-3. These were taken prior to prepping and draping to ensure the ability to obtain satisfactory imaging. |
For the orthogonal view, both axillary views and scapular Y views have been described. Although the scapular Y view is insufficient to judge glenohumeral alignment, it does provide some visualization of sagittal plate alignment of the proximal humerus. More commonly, an axillary view is obtained by abducting the shoulder and rotating the C-arm 90° from the AP image. Getting this view often requires some provisional fixation to be in place to allow abduction of the shoulder. If the surgeon is inexperienced with the procedure or the setup, it is vital that the C-arm is brought in prior to prepping and draping to ensure that appropriate imaging can be obtained (Figure 29-4).
Arm Holder
Intraoperatively, the position of the limb has significant implications for reduction and visualization. Surgical assistants may help manipulate the arm throughout the surgery, but intraoperative arm holders provide the benefit of sustained reduction without the need for extra personnel. In particular, gentle shoulder flexion and traction are useful for many cases, as is the ability to hold the arm in external rotation when fluoroscopically assessing an AP view. Multiple arm-positioning devices are available on the market currently, some using pneumatic technology and others relying on internal gears.
Approach
The two most common approaches to ORIF of proximal humerus fractures are the deltopectoral approach and the anterolateral acromial (deltoid-splitting) approach. Percutaneous and minimally invasive approaches have been described but are less commonly used for plate fixation of the proximal humerus.
The deltopectoral approach is the standard workhorse approach to the shoulder and is familiar to many surgeons for a variety of procedures, including fracture fixation, open instability surgery, and shoulder arthroplasty. It relies on the anterior internervous plane between the deltoid and the pectoralis major muscles, with the cephalic vein retracted with either muscle. The subdeltoid and subacromial space must be mobilized to allow for retractor placement deep to the deltoid and access to the lateral surface of the proximal humerus. The clavipectoral fascia lateral to the conjoint tendon is incised and the interval between the conjoint and the underlying subscapularis can be bluntly developed. The axillary nerve should be identified by visualization or palpation in this interval as it courses deep and lateral underneath the glenohumeral joint. The distal extent of the axillary nerve may also be identified, as it lies deep to the deltoid laterally. At this point, for fractures of the proximal humerus, much of the approach is done and attention can be turned to exposing and cleaning the fracture. Depending on the patient and surgeon preference, the rotator interval can be opened and the long head of the biceps tenodesed as part of the exposure. Some advocate for doing this routinely to eliminate a potential pain generator in the biceps and contributor to posttraumatic contracture in the rotator interval. The other potential benefit in doing so is some degree of access to the glenohumeral joint. If there is minor or peripheral articular involvement, this can often be seen or palpated
through the opened rotator interval. At the end of the fixation, the humeral head can also be palpated to ensure no screw prominence. If further exposure of the articular surface is required, as in a true head-splitting fracture, standard methods of subscapularis mobilization (including a tendon peel or lesser tuberosity osteotomy) can be used14 (Figure 29-6). If a lesser tuberosity fracture is part of the fracture pattern, then it can be utilized as well.
through the opened rotator interval. At the end of the fixation, the humeral head can also be palpated to ensure no screw prominence. If further exposure of the articular surface is required, as in a true head-splitting fracture, standard methods of subscapularis mobilization (including a tendon peel or lesser tuberosity osteotomy) can be used14 (Figure 29-6). If a lesser tuberosity fracture is part of the fracture pattern, then it can be utilized as well.
![]() FIGURE 29-6 Intraoperative image of a head-splitting fracture visualized after subscapularis peel and ORIF.
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