Inadequate oxygenation or ventilation
Airway obstruction
Loss of protective airway reflexes (e.g., depressed cough and gag reflexes)
Excess work of breathing
Nonresponsive and apneic
CONTRAINDICATIONS
Absolute Contraindications
None for unstable patients (i.e., “crash” airway)
Relative Contraindications
In these circumstances one should consider consultation with anesthesiologist/intensivist, alternative techniques, and/or sedation without paralysis
Infectious: Epiglottitis, croup, retropharyngeal abscess, bacterial tracheitis
Noninfectious: Anaphylaxis/angioedema, foreign body, trauma, burns
Congenital anomalies (e.g., cleft palate, micrognathia)
Unanticipated difficult airway (e.g., multiple failed attempts)
RISKS/CONSENT ISSUES
Airway trauma
Arrhythmia (e.g., bradyarrhythmia)
Aspiration of stomach contents
Esophageal intubation
Increase in blood pressure and intracranial pressure (ICP)
Hypoxemia
Pain
LANDMARKS
Anatomical differences in children (FIGURE 89.1):
Larger tongue
Larger and floppy epiglottis
Narrower cricoid ring
Larger occiput
The glottic opening is more cranial and anterior in children and is located at:
C1 in infancy
C3–C5 at age 7
C4–C6 in the adult (Figure 89.1)
Differences are most pronounced under 2 years, transition from 2 to 8 years, then approach small adult anatomy by 8 years
General Basic Steps
Preparation
Preoxygenation
Pretreatment
Protection and positioning
Paralysis and induction
Placement of tube and proof of tube placement
Postintubation management
TECHNIQUE
If crash airway and difficult airway algorithms are not indicated, then rapid sequence intubation (RSI) is the preferred approach. This approach is summarized in seven discrete steps, each beginning with the letter “P.”
Preparation: Directed history, physical examination, indications/contraindications for RSI
Assemble equipment using the “SOAP ME” mnemonic (TABLE 89.1)
Size is best estimated using Broselow tape or centimeter measuring tape
Oral airway
Size using Broselow tape or distance from the angle of the mouth to the ear tragus
Nasopharyngeal airway
Size using Broselow tape, distance from the tip of the nose to the ear tragus, or largest comfortable size that does not produce skin blanching
Laryngoscope blade
Straight/Miller blade traditionally has been preferred to the curved blade for infants and young children. However, either blade can be used in any age group depending on availability and operator comfort.
Endotracheal tube (ETT) size based on Broselow tape or calculated as follows:
Uncuffed: (Age in years/4) + 4 (subtract 0.5−1 for cuffed tube)
S | Suction | Yankaur device (children/adolescents) and/or flexible catheters (infants), suction tubing, wall-mounted suction |
O | Oxygen | Face mask (preferably nonrebreather), oxygen tubing, high-flow oxygen source, Bag/Valve device (with positive-pressure valve) |
A | Airway | Laryngoscope handle with functional light source and blades, endotracheal tubes, airway tape, stylets, oral/nasopharyngeal airways of varying sizes. Rescue equipment (e.g., Bougie, GlideScope, LMA, cricothyrotomy kit, etc.) should be available in case RSI fails. |
P | Pharmacology | Weight-based medications should be prepared in advanced. Agent selection will depend on circumstances and may include sedatives, induction agents, neuromuscular-blocking agents, lidocaine, and atropine. |
ME | Monitoring equipment | Cardiorespiratory monitoring with pulse oximetry and frequent blood pressure checks through postintubation monitoring phase. Following endotracheal tube placement, secondary confirmation with end-tidal CO2 calorimeter (qualitative/semiquantitative) and/or capnography (quantitative) |
LMA, laryngeal mask airway; RSI, rapid sequence intubation. |
Historically, uncuffed tubes were preferred in infants and young children due to high rates of subglottic stenosis. Currently, either tube may be used in any age group if leak pressures are monitored.
Prepare extra tubes, both 0.5 size smaller and larger than estimated
A stylet can be used to provide rigidity (TABLE 89.2)
ETT depth by Broselow tape or calculated (if age >1 year)
Formula (in cm): (Age in years/2) + 10 or Tube size × 3
End-tidal CO2 monitor
If weight <15 kg, use pediatric calorimeter to avoid false negative readings
Have airway alternatives available (e.g., GlideScope, Airtraq, laryngeal mask airway [LMA], Bougie, needle cricothyrotomy equipment)
Preoxygenation
Theoretically, deliver 100% oxygen for 3 minutes. Practically, use nonrebreather facemask (with positive end-expiratory pressure [PEEP] valve) and high-flow nasal cannula once RSI is considered.
If child becomes apneic, use bag valve mask (BVM) ventilation prior to intubation
Perform neck extension and E-C clamp technique with bag-mask ventilation (BMV) if C-spine injury is not suspected
If two providers are available, one person maintains mask seal while the other compresses the bag
Use the rhythm “squeeze, release, release” to allow time for exhalation
Insert an oral airway in an unconscious patient who is difficult to ventilate
Pretreatment: Refers to the administration of medications to attenuate the potential adverse effects of intubation (TABLE 89.3)
Prior recommendations summarized by “LOAD” (Lidocaine, Opioid, Atropine, Defasciculating agent)
No pretreatment agent is recommended routinely for pediatric RSI
Lidocaine: May limit further rise in ICP in cases of head trauma or elevated ICP
No data to suggest or refute use to prevent reflex bronchospasm
Fentanyl: Analgesic effects may decrease the reflex sympathetic response
May cause hypotension or respiratory depression with other sedatives
Atropine: Used for its anticholinergic effects to prevent or treat bradyarrhythmias
Antisialogogue effect is delayed, limiting its use in RSI
Interferes with pupillary response of the neurologic examination after paralysis
Defasciculating agent: “Defasciculating” and “Priming” doses are no longer recommended