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Intraocular Pressure and Oculocardiac Reflex
Intraocular pressure (IOP) is normally 12 to 20 mm Hg. The eye can be considered a hollow sphere with a rigid wall; pressure rises from an increase in volume or a decrease in size.
Things that increase IOP:
• Changing eye shape by blinking (5 mm Hg) or squinting (25 mm Hg)
• Glaucoma through obstructing outflow of aqueous humor
• Ketamine by increasing blood pressure
• Succinylcholine (5–10 mm Hg) by prolonged contraction (5–10 minutes) of extraocular muscles
• Nitrous oxide if given before, during, or after placement of a gas bubble by the ophthalmologist to facilitate vitreous surgery
Things that decrease IOP:
• Volatile anesthetics by decreasing blood pressure and relaxing extraocular muscles
• Intravenous anesthetics, except for ketamine, by the same mechanism
The oculocardiac reflex consists of a trigeminal (V1) afferent and a vagal efferent.
• Triggers: Traction on extraocular muscles, pressure on eyeball, retrobulbar block, eye trauma
• Effects: Nausea, bradycardia, ventricular ectopy, ventricular fibrillation, sinus arrest
• Treatment: Stop the stimulus. Administer anticholinergic agents (atropine, glycopyrrolate). Usually the reflex self-extinguishes, but administration of local anesthetic into the rectus can performed if it does not.