The hands and feet present some novel challenges to wound closure. First, these areas are highly mobile—by their very nature, these locations are under constant stress, so that the dorsal hands are subject to significant stretching when making a fist or grasping an object. Second, these areas are subject to repetitive friction, on the hands when they are put in a pocket or purse and on the feet while wearing shoes. Moreover, since the hands are frequently exposed to bacteria in the course of everyday events and the feet often spend the day occluded and are bathed in a significant bacterial load during showers, these areas also have a theoretically higher risk of postoperative infection.

Due to these considerations, wound repair on the hands and feet is best accomplished by effecting a robust closure with the minimal degree of transepidermal suture placement. As with all anatomic locations, linear closure is generally preferred if at all possible, and the overwhelming majority of defects on the hands and feet may be closed in a linear fashion.

Careful broad undermining is very helpful in these locations where the vasculature is often easily visualized in the subdermal plane. As with all closures, examining the patient throughout their range of motion may be helpful in determining the best axis for closure. Generally, longitudinal closures along the long axis of the hand or foot are favored, both in terms of minimizing tension and mitigating the risk of postoperative lymphedema. That said, individual variations and individual propensities must always be taken into account when designing a closure.