Remember that Bleeding Associated with Direct Thrombin Inhibitors is not Correctable with Protamine, Fresh-Frozen Plasma, or Platelets



Remember that Bleeding Associated with Direct Thrombin Inhibitors is not Correctable with Protamine, Fresh-Frozen Plasma, or Platelets


Michael B. Streiff MD



Thrombocytopenia is a common occurrence among hospitalized patients, particularly among patients in the intensive care unit (ICU). When a patient is diagnosed with, or suspected of having, heparin-induced thrombocytopenia (HIT) type 2, ICU caregivers should be familiar with a clear treatment plan. In addition to discontinuation of all heparin products, therapy for HIT may include alternative intravenous anticoagulants, specifically argatroban or lepirudin. It is important to understand alternatives for therapy and how to manage these and their potential complications.

Jul 1, 2016 | Posted by in ANESTHESIA | Comments Off on Remember that Bleeding Associated with Direct Thrombin Inhibitors is not Correctable with Protamine, Fresh-Frozen Plasma, or Platelets
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