Radiation and radiation injury

Chapter 37
Radiation and radiation injury


John C. White


The threat of use of radiological materials or nuclear weapons is at its highest point since the end of the Cold War. This chapter summarizes the environment, dangers, planning recommendations, and response techniques for EMS personnel when involved as providers or victims in a radiological or nuclear event. Selected resources are identified.


Radiation: definition and effects


Radiation consists of subatomic particles and electromagnetic waves that can interact with matter. Non-ionizing radiation causes excitement of atoms and molecular structures, and ionizing radiation can remove electrons from atoms and break interatomic and molecular bonds, including single- and double- strand breaks of DNA chains. Ionizing radiation has the capability to cause gross surface and subsurface damage, and incrementally impairs the ability of the body to repair those injuries. The latter effect, typically called a “radiation burn,” requires a different medical response than is typical for thermal burns [1].


Ionizing radiation materially damages the immune system, with permanence depending on radiation dose and probabilistic long-term effects, and requires a multifaceted care environment for injury and recovery.


Ironically, medical personnel, who have ample scientific training beyond that of the general public, are not immune to fear of the effects of radiation created by the entertainment industry. This was confirmed at a major “dirty-bomb” drill in North Texas in 2004 [2]. In that exercise, a large sports venue held 2,500 volunteers and the number of EMS personnel as would be present for an event with capacity of 275,000. State authorities secreted minor radiation sources, commonly available at sporting goods stores, on “trauma victims” with moulage wounds. When patients arrived at the 35 participating hospitals with varying levels of trauma, and hospital personnel detected the radiation sources, all closed temporarily (went to “divert” status) due to the presence of contamination. The local public health authority made a decision to require “contaminated” hospitals to continue to accept contaminated patients, because the authority had received radiation training a few weeks prior to the exercise. In a real-life scenario, fear of radiation can negatively affect operations due to reluctance of medical personnel to handle exposed or minimally contaminated patients. In addition, emergency facilities are likely to be overwhelmed with terrified but uninjured citizens.


Normal radiation environment


The human species developed in a radioactive world. Ionizing radiation from the sun, rocks, cosmic rays, and from naturally occurring radioisotopes in the environment has continually bathed all life on earth since life began. The background radiation level of the earth is actually less now than at the generally accepted date of Homo sapiens’ first appearance. Approximately 0.03% of the potassium on the earth is potassium-40 (K-40), a radioactive isotope with a half-life of 109 years, which decays while emitting powerful gamma rays. Since K-40 is ubiquitous, any foods that contain potassium are radioactive, and human bodies are radioactive as well. We live in a constant bath of ionizing radiation, and DNA strand breaks and radiation-generated chemically active free radicals result from this radiation. In addition, granite, which is widely found on the earth’s surface and used in buildings, contains small amounts of uranium, which generates many radioisotopes as it decays. Radon, a radioactive inert gas that accounts for over half the background radiation exposure in the United States, is a product of uranium decay. Ionizing radiation is simply everywhere in our existence. Excessive amounts of radiation are problematic because the physical re- pair mechanisms we have developed to cope with the background radiation on planet earth become over- whelmed.


Radiation threats


Although the Cold War has ended, the threat of nuclear weapons has not. A number of governments and terrorist organizations have clearly stated the intent to acquire and use such weapons as necessary [3]. In addition, the proliferation of radioisotope sources in medicine and industry has provided targets for terrorist organizations. A substantial effort is underway by responsible governments to protect and secure these sources, but it is possible that a determined group could acquire either a nuclear weapon or radioactive materials sufficient to cause massive destruction, or chaos and panic, with resultant societal disruption and significant expense. In addition, routine uses of radiopharmaceuticals in medicine involve transportation of smaller amounts [4]. Accidents happen and emergency medical personnel could easily be called on to treat accident victims or receive them at their facility. To understand this threat and grasp the effects of a detonation of a nuclear weapon in a city, it is useful to view Video Clip 37.1, produced by the US Defense Threat Reduction Agency (http://www.youtube.com/watch?v=nv_q8q6Z9_I).


Types of ionizing radiation


The main types of ionizing radiation are alpha, beta, gamma (and x-ray), and neutron. Each type has specific penetration, and therefore detection, characteristics. Figure 37.1 shows the penetrating capabilities of each in relation to human tissue.

c37-fig-0001

Figure 37.1 Relative penetration in human tissue of ionizing radiation.


What radiation does not do


Much has been made by the entertainment industry of the effects of radiation. Spontaneous immediate mutations, burns, and insidious unknown and scary effects are legion in movies, television, and novels. It is important to understand that immediate, dramatic mutations of anatomy do not occur, and that strange genetic anomalies are seen only in successive generations with large population-level doses. Radiation levels in the global environment were higher in the distant past due to naturally occurring radioactive elements, and recent atmospheric nuclear weapons testing raised the radiation background only slightly. The medical worker responding to a radiological incident may be exposed to a high-radiation environment for a short time, but the somatic effects should be similar to a short period of exposure to other physiological stressors such as heat, chemicals, or other repairable phenomena. Long-term effects of lower doses of ionizing radiation are generally probabilistic, and the immediate needs of a population exposed to radiological weapons or contaminants are evacuation, clean-up, and emergency care.


Resources for the responder


Since the emergency worker has a basic scientific education, understanding of the effects of radiation is somewhat easier to impart than to the general public. It is critical to remember that the effects of radiation are not magic, but are well understood after many years of scientific research. The emergency worker and emergency manager should identify trusted people in the facility or system who can provide accurate and useful evaluation of the risk and give concrete recommendations to ameliorate the radiation effects, while allowing the responder to perform duties. These resources – people whose livelihood depends on the understanding of radiation and its effects – are available in most communities, hospitals, and government entities. Immediate resources include nuclear medicine personnel who handle isotopes, detection equipment, and isotope clean-up on a daily basis, and are required to have detectors in their facility. Others immediately available include the facility’s radiation safety officer or radiological incident manager who have more in-depth knowledge of radiation detection and effects. Also, well-trained hazardous materials response personnel, who have extensive training and hands-on experience with detection equipment, may be available. They may also have detection equipment in mobile units. Well-trained incident management personnel with radiation training who have participated in local, regional, and national exercises, may also be available.


Resources in reserve


Management of a radiological incident requires understanding of the true threat to emergency personnel. An unreasoned response calling for immediate withdrawal of all emergency personnel to extreme distances is unwarranted and possibly negligent. Since fear of radiation is ubiquitous, a radiation specialist may be called on to provide guidance and reasoned response. Such person(s) may not be immediately available, but may be summoned or contacted. It is critical to note that radiation professionals are essential to response organizations when faced with a radiological response. In-depth under- standing of radiological science and knowledge of resources available can save time, money, and possibly lives.


Resources to contact


Every emergency service supervisor should have a list of immediately available contacts who can give concrete applicable advice and information to a responder. Techniques to protect a responder can be simple to implement with available equipment, and responders should be trained in these at every opportunity. Preparation for a radiological emergency is not necessarily an expensive, long-term process, but rather a matter of standard practice modified to fit an additional stressor. Reliable equipment to detect radiation is readily available, portable, and relatively inexpensive. Local medical use of isotopes requires knowledgeable personnel to handle, administer, and detect the isotope. Transportation requires drivers with an understanding of exposure limits and the materials that are being transported. In a massive incident, massive resources must be brought to bear, but immediate local response will be responsible in the first contact with any radiological threat. Local responders must be given clear and proper instruction and training in how to work with and around radiation. Many professional organizations, web sites, and agencies provide detailed information, such as Health and Human Services’ Radiation Emergency Medical Management website (http://www.remm.nlm.gov), and the U.S. Department of Energy, Oak Ridge National Laboratory’s Radiation Emergency Assistance Center/Training Site (REAC/TS) (http://orise.orau.gov/reacts/), which has expert assistance available year-round, 24 hours a day (call 865-576-1005, and ask for REAC/TS).


How to protect yourself


Exposure to ionizing radiation is a manageable risk. A basic understanding of the radiation environment and the dangers therein is your primary tool to manage how you and those you supervise can perform with minimal risk.


Radiation effects can be summarized simply by considering three elements of exposure.



  • Irradiation: radiation enters and passes through the body as a field
  • Contamination: radioactive materials collect on the outside of the body
  • Internal exposure: radioactive materials enter the body

Each has different causes and effects.


Irradiation


Irradiation means that a person or an object is in a field of radiation, and the effects of that radiation can be reduced by the following three methods.


Time – obey the clock


Radiation effects are linearly cumulative. In a uniform field and at a steady distance, 10 minutes of exposure totals twice as much total effective dose equivalent as 5 minutes of exposure. It is important for emergency responders to understand the radiation field emitted by each victim. U.S. Environmental Protection Agency (EPA) guidelines for exposure of emergency responders are shown in Table 37.1.


Table 37.1 EPA emergency action dose guidliness






















Dose limit
(Whole body) Activity Performed
5rem (5.000
mrem) (0.05Sv)
All activities
10 rem (0.1Sv) Protecting major property
25 rem (0.25Sv) Life saving or protection of large populations
>25 rem (>0.25Sv) Life saving or protection of large population,only by volunteers who understand the risks

rem, roentgen equivalent in man/mammal, a measure of exposure; Sv, Sievert. 1 rem = 10 milliSievert (0.01 Sv); 1 Sievert = 100 rem.


If a patient is emitting a radiation field of 100 millirem per hour (1 milliSv), the responder may spend 50 hours on that patient, or work on 50 patients for 1 hour each. For patients with higher radiation field readings, less time is allowed. Obviously, decontamination of the exterior of the patient can reduce the field, but if radioactive shrapnel is present in the patient, danger for surgical teams may exist.


Distance – radiation magic


Every person has at some time cupped his or her hand around a candle flame or come near a hot light bulb. At a short distance, the flame or bulb feels hot. At a 10 cm distance, the heat is greatly reduced, and at 20 cm may be imperceptible. This principle, known as the inverse square law, applies to ionizing radiation (Figure 37.2). Radiation received by any object decreases as the square of the distance from the source. So moving away from the patient, or staying at a distance if your immediate presence is not required for a procedure, dramatically reduces your dose. Combining distance and time planning can extend your time to work on an emergency patient, allow you to work on more patients, and increase the resources for responding to an incident.

c37-fig-0002

Figure 37.2 Distance causes decrease in radiation exposures exponentially.


Shielding – the thicker, the better


For most radiation sources, dense materials provide more shielding than light materials. Alpha particles will not penetrate skin or clothing or paper. Betas can penetrate approximately 1 cm of flesh, but are stopped by most firefighter protective gear. In the event of high-energy neutron radiation, quantities of plastic and water are required for shielding. Shielding against gamma ray penetration requires substantial quantities of concrete, lead, or water. But in an emergency situation, the person of your coworker, who is 90% water, may be something of a shield. So, standing behind a coworker when you are not needed at the immediate site can help lower your dose. Since shielding for many radiation sources is bulky, shielding is usually the least available tool for protection, unless the characteristics of a shield, such as a wall, are known.


Contamination


Radioactive materials that collect on the outside of a person (“contamination”) may be removed by simple mechanical means. Test data from people accidentally exposed to fallout from a nuclear detonation in the Pacific demonstrate that most of the material was re- moved by disposal of/changing clothing [5]. Recently released Army videos show effective “‘decontamination”’ of troops by using brooms to sweep materials from clothing, and describe sufficient reduction of exposures, which confirms that initial fallout or contamination is in sand-sized grains. (Broom Decon Segment Movie – Video Clip 37.2).

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Jun 14, 2016 | Posted by in EMERGENCY MEDICINE | Comments Off on Radiation and radiation injury

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