(1)
Hôpital Ambroise Paré Service de Réanimation Médicale, Boulogne (Paris-West University), France
Electronic supplementary material
The online version of this chapter (doi:10.1007/978-3-319-15371-1_14) contains supplementary material, which is available to authorized users.
A few seconds are sufficient to rule out pneumothorax, less than 1 min to rule it in, at the bedside. This justifies the length of the present chapter.
Chapter 27 will explain how the inclusion of this simple diagnosis can change the habits in several areas of medicine. The present chapter will be as technical and short as possible. Just imagine all situations where the diagnosis of pneumothorax is evoked, or routinely sought for. Just after the usual physical examination (or before, in the case of cardiac arrest), ultrasound will most of the time be the only used modality. Just imagine.
Referring to the air-fluid ratio, pneumothorax is pure air. In the gas-fluid ratio graph (see Fig. 5.2), it is on top. One may consider this diagnosis some sort of a “non-lung” diagnosis. The description of the interstitial syndrome had to be done previously. Note in the graph that the normal lung, which contains minute volumes of fluid, is placed between these two pathological conditions.
Our 5-MHz microconvex probe is ideal for the investigation of pneumothorax.
Warning for the Reader
The diagnosis of pneumothorax – detecting air within air – appeared abstract, not to say fantasy for the experts, even experienced radiologists during decades. This is why even today, many emergency physicians know this potential but do not reach the next step, i.e., taking concrete decisions (chest tube insertion in extreme emergency). Using a methodical approach, the diagnosis can be fully standardized.
Pneumothorax, How Many Signs?
The user will need sequential thinking, i.e., first searching for an A’-profile and then confirming the diagnosis using the lung point. This makes two signs.
The determination of an A’-profile includes two steps: abolished lung sliding, the A-line sign.
The first step, abolished lung sliding, will be studied in two settings: eupnea and dyspnea for simplifying what can be simplified. In Chap. 10, we studied three settings: normal breathing (where everything is easy), very quiet breathing, and dyspnea. We can here consider together two conditions: normal breathing together with very quiet breathing in mechanical ventilation (since none generates the Keye’s sign), opposed to breathing exacerbated by acute dyspnea (with Keye’s sign).
Determination of the A’-Profile
The detection at the anterior chest wall of abolished lung sliding with the A-line sign in a supine or semirecumbent patient defines the A’-profile. Lung ultrasound is an interactive field, with didactic challenges. Here, the challenge comes from the fact that the abolition of lung sliding, obvious in the case of coexisting B-lines, is more subtle to detect in their absence.
Where to apply the probe? The free pneumothorax is a light disorder (principle N°2). In supine patients, it collects at the less dependent area, near the sky [1]. All life-threatening, free cases involve at least the lower half of the anterior chest wall in a supine patient [2]. The probe should be applied at the point nearest to the sky. In extreme emergencies (cardiac arrest mainly), the patient is supine: the lower BLUE-point. In the semirecumbent patient: the upper BLUE-point. For diagnosing minute, apical cases, read Chap. 36.
Abolition of Lung Sliding
Abolition of Lung Sliding in Eupneic Patients: A Nice Basis
Pneumothorax should be learned “slowly.” The abolition of lung sliding, a first step, should be first recognized on nondyspneic patients quietly. Idiopathic cases seen in the ER and cases occurring on mechanical ventilation do not generate dyspnea (nor do patients in cardiac arrest, but it is not the quiet place for learning). In these “pure” conditions, one can see, first on real time, that the pleural line is completely, strikingly standstill. The slightest sign of activity at the pleural line or Merlin’s space should be considered (see again the variants of lung sliding in Chap. 10). Here, nothing is moving. This is definitely not normal at a vital organ, supposed to move all the time. The absence of parietal activity (severe dyspnea) makes the absence of lung sliding more obvious to detect. The absence of dyspnea is recognized on real time by simple observation (Video 14.1). Critical detail explained in Chap. 10: all filters should have been deactivated.
The M-mode analysis in LUCI shows two superimposed, rectangular areas: the upper Keye’s space and the lower M-Merlin’s space (MM-space). They are separated by the pleural line. In a pure pneumothorax, not dyspneic, the absence of motion from the chest wall makes a regular Keye’s space (upper square), and the absence of lung motion makes a regular MM-space (lower square). Consequently, both spaces have exactly the same pattern, resulting in one M-mode stratified pattern, strikingly homogeneous, from top to bottom (the opposite of the usual seashore sign). Reminiscent of stratospheric condensation phenomena of B-17 flying fortresses squadrons in high altitude, this sign was called the stratosphere sign [3] (Fig. 14.1, Video 14.2). Those who really want by any means to call it the barcode sign should see the Fig. 14.2, read its caption (Fig. 14.2), and make their opinion.
Fig. 14.1
The A’-profile, a basic sign of pneumothorax. The ultrasound diagnosis of pneumothorax. The left image shows an A-line. The complete abolition of lung sliding is perfectly demonstrated on the middle image, using the M-mode. This pattern made of exclusively stratified horizontal lines was called the stratosphere sign, an allusion to threatening stratospheric phenomena (right figure)
Fig. 14.2
Barcode sign? This smiling barcode shows that some expressions can confuse. A word should express an idea. Even if referring strictly to traditional barcodes, the image sounds like making nice shopping with the family in a supermarket on a sunny Saturday. The term of stratosphere suggests the threaten of imminent bombing – like pneumothorax, a deadly event. The suggested idea would create confusions when considering the modern barcodes, which actually display the seashore sign. Lastly, one can also just respect the chronology of publications and use the native term. “Barcode” is quicker? The locution “barcode sign” takes 1.40” versus 1.73” for “stratosphere sign,” but the use of ultrasound (instead of radiography or CT) allows to save hours. For 0.33,” we can use the original label – and avoid deadly confusions
We highly advise to take some time for fixing (in one’s brain) the absence of lung sliding on real-time first. The M-mode helps for understanding the pathophysiology of pneumothorax and the difficult cases which will come soon or late. The control of the real-time pattern will be of major use for being operational in a few seconds, as requested in the first step of the SESAME-protocol (cardiac arrest).
Abolition of lung sliding, analyzed in a medical ICU with CT as reference, showed a sensitivity of 95 % [4]. The rules of reviewing are intangible [5]. Yet if rewritten today, the data would be 100 %; see Anecdotal Note 1. In other words, all cases of pneumothorax yield abolition of nondependent lung sliding. The negative predictive value is 100 % [4]. A normal, nondependent lung sliding confidently rules out pneumothorax.
Abolished lung sliding has a poor specificity: it is far from indicating pneumothorax (see Anecdotal Note 2). When ICU controls have no lung disease, ultrasound positive predictive value is 87 % [4]. This rate decreases to 56 % when the control population includes ARDS patients [6]. It falls to 27 % when patients in acute respiratory failure are selected [7]. In ARDS or extensive pneumonia, lung sliding is abolished in more than one-third of cases. For some who believe that abolished lung sliding means pneumothorax, Table 14.1 is a list of many other causes.
Table 14.1
Some of the situations creating abolition of lung sliding
1. Visceral pleura touching the parietal pleura but motionless |
A history of pleurisy, with pleural adhesions |
A history of pneumothorax, with efficient poudrage or pleurodesis |
Acute pleural symphysis, a frequent complication of ARDS and massive pneumonia |
Complete atelectasis |
Massive fibrosis |
Severe acute asthma |
Apnea |
Cardiorespiratory arrest |
Esophageal intubation (bilateral abolition) |
One lung intubation (usually left sided) |
Jet ventilation |
Severe abdominal compartment syndrome |
2. Visceral pleural not touching parietal pleural |
Pleural effusions of any volume |
Pneumothorax |
3. Visceral pleura absent |
Pulmonectomy |
4. Physical impediments |
Parietal emphysema (by preventing clear analysis of the pleural line) |
5. Technical insufficiencies |
Machines, probes, filters (read text) |
How to complicate the procedure?
If the hand of the operator is not standstill, the dynamic information is spoilt (see again Fig. 1.1).
If the scan is transversal, just on a rib, this rib can show a standstill hyperechoic line (with sometimes this perfid pitfall: repetition lines called M-lines, looking like A-lines) (see Fig. 40.3).
If the machine used is a digital unit especially from the first generations, the image resolution will be unsuitable (read Anecdotal Note 3).
Unsuitable probes give unsuitable results. Most phased-array cardiac probes are not adequate to study lung sliding and the dyspnea at the superficial tissues. Linear probes in bariatric patients and abdominal probes in skinny patients make the same issues.
Abolition of Lung Sliding in Dyspneic Patients: A Higher Step in the Learning Process
The ultrasound diagnosis of pneumothorax is the science of standstillness. A dyspneic patient who tries to survive by recruiting the accessory muscles is not standstill at all. Examining the pleural line in such patients obeys in some sort to the rules of shooting from a mobile point to a mobile target (dogfight). A pneumothorax generates no movement, and a dyspnea generates hectic movements. This latter dynamics from superficial areas will parasite the characteristic standstill sign at the pleural line. The operator must detect a standstillness (at the pleural line) inside a hectic, moving area: an “absolute quandary?”
A standardized approach, using the M-mode and the concept of the Keye’s space, gives the answer. The phenomenon observed on M-mode can be related to a column of sand. The top of this column is located above the pleural line, inside the Keye’s space: this cannot be a seashore sign. A seashore sign would by definition begin at the very pleural line, not 1 mm above, not 1 mm below, spreading below homogeneously. Here, the dynamic comes from the contraction of the parietal muscles (pectoral, intercostal). The sand visible at the Keye’s space, meaning severe dyspnea, is called the Keye’s sign (see details in Chap. 10). Now, the whole of the sand column will be analyzed. In the case of pneumothorax, this sandy image will cross the pleural line without any change, even slight. This is the Avicenne sign (conceived in Avicenne Hospital) (Fig. 14.3, Video 14.3). The Avicenne sign demonstrates that, in spite of the diffuse movement coming from the muscular recruitment above the pleural line, lung sliding is definitely abolished.
Fig. 14.3
The Avicenne sign. Which clinical elements can be extracted from these static views? First (left image, a), real time, this is lung ultrasound, with a bat sign. There is no B-line in the Merlin’s space. Pneumothorax is not excluded. On the middle image (b), M-mode, a turbulence is seen (arrows), filling the Keye’s space, above the pleural line. It descends without any change when crossing the level of the pleural line (the marked horizontal white line, at cm 2.2). This M-mode sign has been coined the Avicenne sign. It has the meaning of a muscular contraction due to severe dyspnea, but also in fine, of an abolished lung sliding. Pneumothorax is fully possible (to be confirmed using the lung point). On real time, this phenomenon can be difficult to see, and here, M-mode is of real help. The right image (c) shows for comparison a Keye’s sign and a seashore sign: no pneumothorax