Pain

Chapter 4 Pain





WHAT IS PAIN?


Pain is caused by the stimulation of nociceptors. These receptors are usually stimulated by chemicals such as substance P, bradykinin, and histamine, which excite the nerve endings. Pain is elicited by three different classes of stimuli: mechanical, chemical, and thermal. Soft tissue pain is caused by the chemicals released from illness, injury, or from mechanical irritation caused by cumulative stress, microinflammation, or extreme heat or cold. Emotional or psychological stress, called autonomic disturbances, can trigger pain by causing an increase in motor tone of muscles – changes in fascial tone and shifts in fluid flow affecting oxygen and nutrient delivery and waste removal.


Pain of somatic origin and from the viscera sends impulses to the limbic and hypothalamic areas of the brain and may be responsible for emotional reactions of anxiety, fear, anger, and depression. In addition, the brain inhibits or enhances a reaction to pain. This can explain why people can sometimes ignore pain and why fear and anxiety can exaggerate pain. How a person responds to pain is called pain tolerance. How a person interprets the pain sensation increases or decreases tolerance. Intervention that changes perception and meaning of pain can increase tolerance, allowing an individual to have better coping strategies in response to pain stimuli. This is a very important point for how people learn to cope with the chronic pain associated with headaches and neck dysfunction.


Pain receptors are found in almost every tissue of the body and may respond to any type of stimulus. Because of their sensitivity to all stimuli, pain receptors perform a protective function by identifying changes that may endanger the body. When stimuli for other sensations, such as touch, pressure, heat, and cold, reach a certain intensity, they stimulate the sensation of pain as well. Excessive stimulation of a sensory organ causes pain. Additional stimuli for pain receptors include excessive distension or dilation of a structure, prolonged muscular contractions, muscle spasms, inadequate blood flow to tissues, or the presence of certain chemical substances. Pain receptors can become sensitized, which results in fewer stimuli necessary to cause pain sensation.



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Injured tissue may release prostaglandins, making peripheral nociceptors more sensitive to the normal pain response (hyperalgesia). Aspirin and other nonsteroidal anti-inflammatory drugs (often referred to as NSAIDs) inhibit the action of prostaglandins and reduce pain.


The point at which a stimulus is perceived as painful is called the pain threshold. This varies somewhat from individual to individual. One factor affecting the pain threshold is perceptual dominance, in which the pain felt in one area of the body diminishes or obliterates the pain felt in another area. Not until the most severe pain is diminished does the person perceive or acknowledge the other pain. This mechanism is often activated with massage application that produces a ‘good hurt’.


Pain tolerance refers to the length of time or intensity of pain that the person endures before acknowledging it and seeking relief. Unlike the pain threshold, pain tolerance is more likely to vary from one individual to another. A person’s tolerance to pain is influenced by a variety of factors, including personality type, psychological state at the onset of pain, previous experiences, sociocultural background, and the meaning of the pain to that person (e.g., the ways in which it affects the person’s lifestyle). Factors that decrease pain tolerance include repeated exposure to pain, fatigue, sleep deprivation, and stress; warmth, cold, distraction, alcohol consumption, hypnosis, and strong spiritual beliefs or faith all act to increase pain tolerance.



ORIGINS AND CLASSIFICATION OF PAIN


The origins of pain can be divided into two types, somatic and visceral. Somatic pain arises from stimulation of receptors in the skin (superficial somatic pain) or from stimulation of receptors in skeletal muscles, joints, tendons, and fascia (deep somatic pain). Visceral pain results from stimulation of receptors in the viscera (internal organs).


Pain is usually classified as acute, chronic, intractable, phantom, and referred. Pain basically results from a series of exchanges involving three major components: peripheral nerves, spinal cord, and brain.






Peripheral nerves


Peripheral nerves encompass a network of nerve fibers that branch throughout the body. Attached to some of these fibers are special nerve endings (nociceptors) that can sense an unpleasant stimulus, such as a cut, burn, or painful pressure.


There are millions of nociceptors in the skin, bones, joints and muscles, and in the protective membranes around the internal organs. Nociceptors are concentrated in areas more prone to injury, such as the fingers and toes. There may be as many as 1300 nociceptors in just 1 square inch of skin. Skin stimulation during massage that is intense enough to stimulate the ‘good hurt’ response causes the nociceptors to fire. This is one of the mechanisms of counterirritation. This is also a major component of massage benefits for pain management.


Muscles, protected beneath the skin, have fewer nerve endings. Internal organs, protected by skin, muscle and bone, have even less. Some nociceptors sense sharp blows, others heat. One type senses pressure, temperature, and chemical changes. Nociceptors can also detect inflammation caused by injury, disease or infection. Massage that addresses these receptors must have enough depth of pressure to elicit a response.


When nociceptors detect a harmful stimulus, they relay their pain messages in the form of electrical impulses along a peripheral nerve to the spinal cord and brain. Sensations of severe pain are transmitted almost instantaneously. Dull, aching pain – such as an upset stomach, earache, or joint aching – is relayed on fibers that transmit at a slower speed.





Jun 14, 2016 | Posted by in PAIN MEDICINE | Comments Off on Pain

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