Obstetric Anesthesia

Analgesia for Labor

Influence of epidural dexamethasone on maternal temperature and serum cytokine concentration after labor epidural analgesia

Wang L-Z, Hu X-X, Liu X, et al (Jiaxing Maternity and Child Health Care Hosp, China) Int J Gynaecol Obstet 113:40-43, 2011^§

Abstract

Objective

To evaluate the effects of epidural dexamethasone on maternal temperature and serum cytokine levels after labor epidural analgesia.

Methods

Sixty healthy term nulliparas in spontaneous labor were randomized to receive epidural analgesia alone using bupivacaine 0.125% and fentanyl 1 μg/mL (group I) or epidural analgesia combined with dexamethasone 0.2 mg/mL (group II) (n = 30 per group). Maternal tympanic temperature was measured before epidural analgesia and hourly thereafter until delivery. Maternal and cord venous blood were sampled for analysis of interleukin-6 (IL-6), tumor necrosis factor-α, and interleukin-10 levels.

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