of a dietary portfolio of cholesterol-lowering foods given at 2 levels of intensity of dietary advice on serum lipids in hyperlipidemia: a randomized controlled trial

Studies of Outcomes, Risks, Costs, and Benefits


Effect of a dietary portfolio of cholesterol-lowering foods given at 2 levels of intensity of dietary advice on serum lipids in hyperlipidemia: a randomized controlled trial


Jenkins DJ, Jones PJ, Lamarche B, et al (St Michael’s Hosp, Toronto, Ontario, Canada; Univ of Toronto, Ontario, Canada; Laval Univ, Quebec City, Canada; et al) JAMA 306:831-839, 2011§



M.F. Roizen, MD



Evidence Ranking


• A



Expert Rating


• 3



Abstract



Context


Combining foods with recognized cholesterol-lowering properties (dietary portfolio) has proven highly effective in lowering serum cholesterol under metabolically controlled conditions.



Objective


To assess the effect of a dietary portfolio administered at 2 levels of intensity on percentage change in low-density lipoprotein cholesterol (LDL-C) among participants following self-selected diets.



Design, Setting, and Participants


A parallel-design study of 351 participants with hyperlipidemia from 4 participating academic centers across Canada (Quebec City, Toronto, Winnipeg, and Vancouver) randomized between June 25, 2007, and February 19, 2009, to 1 of 3 treatments lasting 6 months.

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Jan 28, 2017 | Posted by in ANESTHESIA | Comments Off on of a dietary portfolio of cholesterol-lowering foods given at 2 levels of intensity of dietary advice on serum lipids in hyperlipidemia: a randomized controlled trial

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