Table 11.2 provides a comprehensive guide to the relevant monitoring required when a patient is receiving TPN. In particular the nurse should be alert to the possible complications of TPN.
Reproduced by permission of Butterworth Heinemann Elsevier, from Bersten and Soni (2009).
Monitoring | Specific tasks |
Regular clinical | Temperature Blood pressure Pulse rate Respiratory rate Fluid balance Blood glucose (4-hourly when commencing feed) |
Daily (at least) | Fluid balance review Nutrient intake review Urea, electrolytes and creatinine Blood glucose |
Weekly (at least) | Full blood count Coagulation screen Weight Liver functions tests Serum calcium/magnesium/phosphate |
As indicated | Zinc Uric acid |
During TPN administration, there is a significant risk of morbidity through sepsis, metabolic and mechanical problems (Sabol and Steele 2009; Ziegler 2009). Mechanical complications include: pneumothorax, bleeding, thrombus formation, sepsis; catheter related, metabolic; overfeeding (excess dextrose, fat, calories and re-feeding syndrome (rapid feeding of patients with pre-existing malnutrition) (Ziegler 2009). In addition, rebound hypoglycaemia can occur if the TPN infusions are abruptly stopped. Regular urinalysis and blood glucose monitoring are therefore important.
The function of the gut should be monitored so that conversion to enteral nutrition can be initiated as soon as possible. TPN should be gradually withdrawn in order to avoid complications, e.g. rebound hypoglycaemia. In some instances and enteral and concomitant parenteral feeding may be necessary to meet metabolic demands.
Best Practice – Parenteral Feeding
Only use when enteral route is not possible
Do not use feed bag if there are signs of contamination
Administer feed following local protocols
Ensure that entire infusion line is dedicated to parenteral nutritional use
Ensure that feed and tubing are regularly changed (usually every 24 hours)
Never add anything to a bag of TPN
Monitor patient’s blood chemistry
Monitor blood sugar 2-hourly when first initiated
Monitor patient for complications of parenteral nutrition, particularly infection
Regularly flush line when not in use to maintain patency
Avoid breaks in circuit
Monitor gut function so that enteral feeding can be started as soon as possible