(1)
Royal Free NHS Foundation Trust, London, UK
Secondary dysmenorrhea is associated with underlying pelvic pathology and can lead to ED attendance.
Causes of secondary dysmenorrhoea
Lower genital tract:
Painful cryptomenorrhoea:
Imperforate hymen
Transverse vaginal septum
Congenital absence of cervix
Acquired cervical stenosis
Uterus:
Congenital uterine abnormalities: non-communicating horn
Adenomyosis
Pedunculatedsubmucous fibroid
Endometrial polp
Intrauterine adhesions
Intrauterine device use
Pelvis:
Endometriosis (may be associated with dysmenorrhoea, dyschezia, chronic pelvic pain, infertility, haematuria, and rectal bleeding)
Chronic pelvic inflammatory disease
Pelvic adhesions
Key historical features in secondary dysmenorrhoea
Typically, the onset is after several years of painless periods
The pain may not respond to non-steroidal anti-inflammatory agents or oral contraception
Gynaecological symptoms: dyspareunia; abnormal vaginal discharge; menorrhagia; inter-menstrual or post-coital bleeding
Gastrointestinal symptoms: rectal pain and bleeding (endometriosis)
Causes of abnormal vaginal bleeding
Abnormal menstrual bleeding:
Excessive
Reduced
Inappropriate (by age)
Non-menstrual bleeding:
Post-coital
Intermenstrual
Postmenopausal
Categories of excessive vaginal bleeding
Menorrhagia: excessive menses (>80 ml monthly menstrual loss, ie >90th centile for menstrual blood loss) but normal cycle (>7 days with one or more days of excessive loss)
Short cycle (<21/7) but normal menses (polymenorrhoea)
Short cycle + excess bleeding (polymenorrhagia)
Excessive menses at long intervals
Metrorrhagia: irregular intervals with excessive menses
Causes of abnormal genital tract bleeding in the reproductive age group
Pregnancy –related
Early pregnancy
Implantation bleeding
Pregnancy failure: miscarriage (haemodynamic status; state of internal os; products of conception)
Ectopic pregnancy
Gestational trophoblastic disease (molar pregnancy)
Later pregnancy (antepartum haemorrhage-from 24 weeks of pregnancy)
Placenta praevia: painless bleeding; soft, non-tender uterus; high presenting part or malpresentation
Placental abruption: severe abdominal or back pain; uterine contractions may be present; uterine tenderness
Vasa praevia
Uterine inversion
Retained placenta
Endometritis
Non-pregnancy-related
Dysfunctional uterine bleeding: anovulatory bleeding; corpus luteum dysfunction.
Structural abnormalities
Genital tract neoplasia: cervix; endometrium; vulva; vagina; Fallopian tube
Polyps: cervix; endometrium
Infection:
Endometritis
Atrophic endometritis (post-menopausal)
Cervicitis
Endocrine dysfunction:
Hypothalamus/pituitary
Adrenal
Thyroid
Foreign bodies
Iatrogenic:
Intrauterine devices
Hormonal treatment
Blood dyscrasias:
Platelet disorders:idiopathic thrombocytopenic purpura
Clotting factor abnormalities: von Willebrand disease
Symptoms accompanying menorrhagia that indicate significant pathology
Malignancy: persistent inter-menstrual or post-coital bleeding; unexplained vulval lump or vulval bleeding due to ulceration
Other structural disease: pelvic pain; pressure symptoms
Causes of premenarcheal genital tract bleeding
Trauma
Lower genital tract neoplasm: cervix; vagina
Foreign body
Exogenous oestrogen
Sporadic gonadotrophin surge
Precocious puberty or pseudopuberty
Gastrointestinal bleeding
Urinary tract bleeding
Causes of menorrhagia
Dysfunctional uterine bleeding (60%)
Other gynaecological causes (35%)
Uterine/ovarian tumours
Endometrial hyperplasis
Endometriosis
Pelvic inflammatory disease
Intrauterine contraceptive device
Endocrine and haematological causes (<5%)
Thyroid disease: hypothyroidism; hyperthyroidism
Platelet problems: thrombocytopenia
Clotting abnormalities: haemophilia; von Willebrand disease; anticoagulationStay updated, free articles. Join our Telegram channel
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