(1)
Critical Care Medicine and Pain Medicine, Boston Children’s Hospital, Boston, MA, USA
(2)
Harvard Medical School, Boston, MA, USA
Questions
- 1.
Which of the following are considered risk factors for the development of tuberculosis (TB) in children?
- 1.
HIV infection
- 2.
Exposure to an infectious adult
- 3.
Malnutrition
- 4.
Passive exposure to cigarette smoke
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 2.
Tuberculosis infection may involve which of the following organs/systems?
- 1.
The lungs
- 2.
The bones
- 3.
The CNS
- 4.
The kidneys
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 3.
What percentage of immunocompetent adults infected with tuberculosis will develop active disease during their lives?
- A.
100 %
- B.
50 %
- C.
25 %
- D.
5 %
- E.
2 %
- A.
- 4.
Which of the following factors may affect the accuracy of the Mantoux test (the intradermal injection of 5 TU of PPD in 0.1 ml diluent)?
- 1.
Concurrent penicillin treatment
- 2.
The presence of other infections
- 3.
Presence of fever >38 °C
- 4.
Prior BCG vaccination
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 5.
Group A beta-hemolytic streptococci cause:
- 1.
Scarlet fever
- 2.
Tonsillitis
- 3.
Impetigo
- 4.
Erysipelas
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 6.
Which one of the following is true regarding the non-suppurative complications of group A beta-hemolytic infections?
- 1.
Rheumatic fever may develop after tonsillitis.
- 2.
Neither nephritis nor rheumatic fever develops after impetigo.
- 3.
Rheumatic fever is caused by the same strains of the organism as nephritis.
- 4.
Nephritis develops only after scarlet fever rashes.
- 1.
- 7.
Helicobacter pylori (H. pylori):
- 1.
Has been cultured from children with hypertrophic pyloric stenosis
- 2.
Has been implicated as a cause of chronic abdominal pain in children
- 3.
Generally causes watery, but not bloody, diarrhea
- 4.
Is considered a contributing factor in the pathogenesis of peptic ulcer
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 8.
Colitis due to infection with toxigenic Clostridium difficile:
- 1.
Is due to overgrowth of the organism after antibiotic therapy
- 2.
Is characterized by watery, often bloody, diarrhea
- 3.
Is due to the toxins produced by C. difficile
- 4.
Can also be caused by ingestion of preformed toxin found in poorly refrigerated food
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 9.
Regarding the clinical manifestations of bacterial meningitis beyond the neonatal period:
- 1.
Focal neurologic signs are seen in 10–15 % of cases.
- 2.
If seizures occur, it is very likely that the child will be left with a permanent seizure disorder.
- 3.
Fever need not be present.
- 4.
Photophobia, due to inflammation of the optic nerve, may lead to permanently impaired vision.
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 10.
Regarding the prognosis of bacterial meningitis beyond the neonatal period:
- 1.
Some degree of hearing loss is seen in approximately 10 % of survivors.
- 2.
Neurologic abnormalities seen shortly after the onset of meningitis may resolve over time.
- 3.
The mortality rate is 1–5 %.
- 4.
Brain abscesses are commonly seen during the course of antibiotic therapy.
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 11.
The hemolytic uremic syndrome:
- 1.
Typically has a prodrome of 3–5 days of diarrhea
- 2.
May include neurologic dysfunction such as seizures or coma in its presentation
- 3.
May include hypertension as part of its presentation
- 4.
Generally is treated with supportive care (careful fluid and electrolyte management, dialysis, and transfusion as needed)
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 12.
Children with the hemolytic uremic syndrome (HUS):
- 1.
May have had infection with E. coli, Shigella, or Salmonella
- 2.
Have anemia, thrombocytopenia, and low WBC counts due to bone marrow failure
- 3.
Are generally younger than 5 years of age
- 4.
Are best treated with IV immunoglobulin
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 13.
In children with a temperature greater than 39 °C without a source for the fever:
- 1.
Bacteremia will likely occur in 1–5 % of cases.
- 2.
Bacteremia, if it occurs, will most often be due to Streptococcus pneumoniae.
- 3.
The risk for occult bacteremia is greatest among those younger than 24 months.
- 4.
Almost all of the children who have bacteremia will develop purulent complications.
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 14.
Which of the following are seen relatively often in children with immunodeficiencies?
- 1.
Growth failure
- 2.
Chronic diarrhea
- 3.
Skin rashes
- 4.
Recurrent or chronic infections
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 15.
Scabies:
- 1.
Is characterized by beefy red skin with satellite lesions
- 2.
Has 1–2 mm red papules which may be excoriated or crusted
- 3.
Is caused by contact with an allergen
- 4.
Is a pruritic rash, particularly at night
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 16.
Urticaria (hives) in children may be associated with:
- 1.
Airway edema
- 2.
Contact with a food or chemical
- 3.
Exposure to cold
- 4.
Exercise
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 17.
Urticaria:
- 1.
Is an evanescent rash consisting of red-pink wheals
- 2.
May be treated with PO diphenhydramine
- 3.
Is commonly associated with beta-streptococcal infections
- 4.
Is especially common in children with abnormalities in T-cell function
- A.
1, 2, 3
- B.
1, 3
- C.
2, 4
- D.
4 only
- E.
All of the above
- A.
- 1.
- 18.
Get Clinical Tree app for offline access
The first teeth to erupt, the lower central incisors, do so at the age of:
- A.
4 months
- B.
7 months
- C.
- A.