Fetal Surgery




© Springer International Publishing AG 2017
Robert S. Holzman, Thomas J. Mancuso, Joseph P. Cravero and James A. DiNardo (eds.)Pediatric Anesthesiology Review10.1007/978-3-319-48448-8_10


10. Fetal Surgery



Joseph P. Cravero1, 2  


(1)
Department of Anesthesiology, Perioperative, and Pain Medicine, Boston Children’s Hospital, Boston, MA, USA

(2)
Harvard Medical School, Boston, MA, USA

 



 

Joseph P. Cravero



Keywords
PregnancyFetusExit procedureTocolysisUteroplacental blood flowUterine atonyMyelomeningoceleMethergine


You are asked to provide anesthesia for a 30-year-old female who is currently pregnant with a 22-week fetus who has a myelomeningocele. The surgery team would like to correct the defect at this point to avoid neurologic damage that will result from prolonged exposure of the fetal neural structures to amnionic fluid. The baby will be brought ex utero for the procedure and then returned for the duration of the gestation.


Preoperative Preparation



Questions





  1. 1.


    What are the maternal and fetal physiological considerations that should be taken into account prior to beginning this procedure?

     

  2. 2.


    How do you maintain fetal well-being during the course of the procedure? What are the primary considerations for maintaining adequate blood flow?

     

  3. 3.


    How would you prepare the patient(s) for surgery and anesthesia? What kind of monitors should be in place?

     

  4. 4.


    What is the normal fetal oxygen saturation? How would you monitor heart function?

     


Preoperative Preparation



Answers





  1. 1.


    Pregnancy affects many aspects of maternal physiology. Oxygen demand is greater so precautions must be taken to prevent periods of prolonged apnea or hypoventilation. Capillary permeability increases so the risk of pulmonary edema is elevated – particularly in the setting of magnesium used for tocolysis. The weight of the gravid uterus can decrease venous return so left uterine displacement is an important consideration. In terms of the fetus, exposure to stress has been associated with increased cortisol and other stress hormones. Opiates have been shown to attenuate this response – so there is no doubt about the need for anesthesia in the fetus. The fetus requires less anesthesia than a child, but it should be recognized that although inhaled agents readily cross the placenta, they do not reach maternal levels for a prolonged period of time. The fetal heart has less contractile tissue and is sensitive to the cardiac depressant effects of anesthesia. When combined with fetal manipulations during surgery, hypotension, bradycardia, and cardiovascular collapse are a significant consideration. The circulating volume of a fetus is very small and blood loss is poorly tolerated. Fetal skin is not yet mature and subcutaneous tissue is lacking – thus leading to the tendency for hypothermia if exposed to ambient temperature environment for any period of time.

     

  2. 2.


    Fetal circulation is dependent on uteroplacental blood flow. Maternal volume status and blood pressure must be optimized. Uterine tone increases during contractions with a corresponding increase in vascular resistance. It is therefore critical to keep the uterus relaxed. Kinking of the umbilical cord must be avoided and corrected if it occurs. Increased pH and hypocarbia will decrease uterine blood flow and result in fetal hypoxia.

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Oct 9, 2017 | Posted by in Uncategorized | Comments Off on Fetal Surgery

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