Disorder of Ear, Nose, and Sinus



Disorder of Ear, Nose, and Sinus


Hartmut Göbel

Robert W. Baloh



EARS

International Headache Society (IHS) code and diagnosis: 11.4 Headache attributed to disorder of ears

World Health Organization (WHO) code and diagnosis: G44.844 Headache associated with disorders or diseases of the ear and mastoid process



  • H60: Otitis externa


  • H61: Other disorders of external ear


  • H62*: Disorders of external ear in diseases classified elsewhere


  • H65: Nonsuppurative otitis media


  • H66: Suppurative and unspecified otitis media


  • H68: Eustachian salpingitis and obstruction


  • H69: Other disorders of eustachian tube


  • H70: Mastoiditis and related conditions


  • H71: Cholesteatoma of middle ear


  • H75*: Other disorders of middle ear and mastoid in diseases classified elsewhere


  • H92: Otalgia and effusion of ear


  • H92.0: Otalgia


EPIDEMIOLOGY

No systematic population-based studies of the epidemiology of the different forms of pain associated with diseases of the ears are known. Only studies of individual clinical cases exist. A Spanish study analyzed the epidemiology of acute otitis media in 20,532 schoolchildren over a 6-month period (8). The study was based on a questionnaire sent to all Spanish pediatricians. The most frequent symptom of otitis media, in 92.7% of cases, was earache. In 45.6% of cases, the symptoms occurred on both sides.

In general, earache is a frequent symptom, especially in children. An analysis of the most frequent symptoms in the emergency department of a university pediatric clinic showed that five symptoms were responsible for 40% of all consultations: high temperature, vomiting or diarrhea (or both), infection of the upper respiratory tract, earache, and skin rashes (30). An Austrian study investigated symptoms in children in connection with swimming in lakes open for public bathing. At 32.4%, otalgia was the most common symptom. The study also found a significant correlation with rhinitis, conjunctivitis, coughing, and sore throat (36.5%) (10). Otitis media is thus one of the most frequent causes of earache.

Earache, otorrhea, and otorrhea with bleeding are the principal symptoms of patients with tumors of the middle ear (17). A study that analyzed the symptoms of nasopharyngeal carcinomas revealed that deafness and earache, encountered in 85% of cases, were the most common symptoms besides swelling of the throat. The earache had been present for as long as 9 months before a correct diagnosis was made (31). The most common cause of intracranial abscesses, with a frequency of 73%, was chronic infection of the middle ear. The clinical symptoms are characterized by chronic otitis with otorrhea, earache, headache in the region of the temples, high temperature, nausea, and vomiting (6,19).


ANATOMY AND PATHOLOGY

Local structural lesions in the region of the pinna, external ear canal, tympanic membrane, and middle ear may give rise to primary otalgia. Only about 50% of all earaches are due to structural lesions of the external or middle ear. Disorders outside this region may lead to referred otalgia as a result of radiation of pain into the ear region. Sensory fibers of the fifth, seventh, ninth, and tenth cranial nerves project into the auricle, external auditory canal, tympanic membrane, and middle ear (Table 123-1). For this reason, referred pain from remote structural lesions in these anatomic regions can be felt as referred otalgia.









TABLE 123-1 Sources of Referred Otalgia











































Nerve


Location of Lesion


Common Disorders


Fifth cranial nerve, mandibular division (auriculotemporal branch)


Teeth


Pulpitis, periapical dental abscess



Oral cavity


Glossitis, osteitis, intraoral abscess, benign or malignant growth



Sinus


Inflammation, benign or malignant growth



Temporomandibular joint (TMJ)


Dental malocclusion, arthritic process


Seventh cranial nerve, (Nervus intermedius branch)


Middle ear


Ramsey-Hunt syndrome (herpes zoster oticus)


Ninth cranial nerve (Jacobson’s nerve)


Nasopharynx, eustachian tube, palatine tonsils, tongue


Inflammation, benign or malignant growth


Tenth cranial nerve (Arnold’s branch)


Hypopharynx, larynx, nasopharynx


Benign or malignant growth


Second and third cervical roots (greater auricular nerve and lesser occipital nerve)


Base of skull


Abscess, inflammation, and tumor; thyroid carcinoma; lesions of nasopharynx and oropharynx


Cranial neuralgia


See Chapter 126




PATHOPHYSIOLOGY


Primary Otalgia


Pinna

Primary pinna pain in the first instance may be caused by injuries or traumas that may result in laceration, burns, frostbite, infections, or abscesses. In the case of persistent minor lesions, a biopsy should be performed, because these lesions may obscure a malignant new growth, especially a basal cell carcinoma, a squamous cell carcinoma, or small benign growths.


External Ear Canal

The external ear canal is a particularly common source of primary earache. External otitis arises from an acute inflammatory process after ear trauma, inadequate cleansing of the external ear canal, or lengthy contact with liquid in bacterially contaminated water, especially in bathing lakes or swimming pools (swimmer’s ear). External otitis, however, may occur on the basis of a chronic middle ear infection or as a result of a malignant new growth in the external ear canal. Malignant external otitis may be observed, particularly in patients with diabetes mellitus or an immune deficiency. In addition to severe earache with reddening of the pinna and inflammation of the periauricular region, there is heightened sensitivity to touch, swelling of the pinna, and swelling of the mastoidale. A general feeling of malaise and elevated temperature also may occur.

Ear wax also may be responsible for earache and pressure in the ear. The same applies to foreign bodies in the ear canal. Removal of such objects must be undertaken with the utmost care and precision to avoid injuring the external ear canal and the tympanic membrane. Another cause of earache may be benign or malignant new growth in the external ear canal. In case of doubt, a biopsy should be performed. Neoplasms are rare and in most cases take the form of a squamous cell carcinoma or adenocarcinoma.


Middle Ear and Mastoid

An acute infection of the mucous membrane of the middle ear in the form of acute otitis media usually stems from an infection of the upper air passages with dysfunction of the eustachian tube. Rhinitis and adenoid inflammation also may cause acute otitis media. The disease usually is accompanied by an elevated temperature and infection of the upper respiratory tract. Examination reveals reddening and swelling of the tympanic membrane. Occasionally, a purulent discharge is present.

Acute mastoiditis may complicate otitis media if not treated properly. Typically, a highly sensitive and swollen mastoidale is present. Obstruction of the pinna, a reddened and bulging tympanic membrane, and purulent otorrhea are typical examination findings. An initial slight ache increases sharply with the purulent inflammation and radiates into the entire neck and head area.


Petrositis

Inflammatory spread to the petrous bone from otitis can occur and would be complicated by meningitis or an intracranial or extradural abscess. Pain can be referred to the temporoparietal, retro-orbital, and temporal regions. Lesions of the cranial nerves also may be observed. The
classic triad of findings associated with lesions of the petrous apex (Gradenigo syndrome) includes (1) deep retro-orbital pain, (2) paresis of the ipsilateral lateral rectus muscle, and (3) otorrhea.


Acoustic Neuroma

Acoustic neuroma (vestibular schwannoma) is a benign tumor of the neural sheath of the eighth cranial nerve and its peak incidence is mostly between the ages of 30 and 40. Women are affected more frequently than men. Tinnitus, hearing loss, and tingling or deep pain in the ear are early symptoms. Over time, these symptoms may be joined by vertigo. As the tumor slowly grows out of the internal auditory canal into the cerebellopontine angle it can compress the fifth and seventh cranial nerves, producing numbness and weakness of the face. Dysarthria, ataxia, and incoordination also may be observed due to compression of the adjacent cerebellum. Obstruction of cerebrospinal fluid circulation may give rise to headache from increased intracranial pressure with nausea, vomiting, and neuropsychologic deficits.


Traumas

Trauma of the tympanic membrane may be caused by direct mechanical damage with fracture of the temporal bone or by external compression. Foreign bodies also may give rise to traumatic perforation of the tympanic membrane. Rupture of the tympanic membrane also may occur as a result of increased pressure in the external ear canal, for example, as a result of a slap on the ear with an open hand. Earache and hearing loss occur as typical symptoms.

Barotrauma is caused by elevated pressure in the external ear canal, for example, by sudden changes of pressure in an airplane or during diving activities. Symptoms include localized or radiating pain in the region of the middle ear but also along the fifth, ninth, and tenth cranial nerves. Hematotympanum and conduction deafness also may occur.

Trauma of the temporal bone most commonly leads to a longitudinal fracture, which may result in rupture of the tympanic membrane. Depending on its course, the fracture may lead to paralysis of the seventh cranial nerve. Pain radiates into the area of distribution of the fifth, ninth, and tenth cranial nerves. In addition, conduction deafness or facial paralysis may be observed. Given appropriate localization, drainage of cerebrospinal fluid or blood from the external ear canal also may occur. An ecchymosis over the mastoid (Battle sign) is an indication of a fracture of the base of the skull.

In a transverse fracture, there may be no rupture of the tympanic membrane, depending on the course of the fracture line. If the internal auditory canal is involved, lesions of the seventh and eighth cranial nerves may occur with sensory-neural hearing loss, vertigo, and facial paralysis.


Benign and Malignant New Growth in the Middle Ear

A growth in the middle ear is rare but always should be considered if a chronic middle ear infection or a polypoid lesion does not respond to adequate treatment and chronic pain continues. The pain is typically localized, but it may radiate into the areas of distribution of the fifth, ninth, and tenth cranial nerves. Examination reveals local ulceration, which should be subjected to biopsy.


Secondary or Referred Otalgia

Referred otalgia may arise from structural lesions in the region of the branches of the fifth, seventh, ninth, and tenth cranial nerves and of the second and third cervical roots (Table 123-1).


CLINICAL FEATURES

IHS diagnostic criteria for headache attributed to disorder of ears (Revised International Classification for Headache Disorders [ICHD-II]) (14) are as follows:

A. Headache accompanied by otalgia and fulfilling criteria C and D.

B. Structural lesion of the ear diagnosed by appropriate investigations.

C. Headache and otalgia develop in close temporal relation to the structural lesion.

D. Headache and otalgia resolve simultaneously with remission or successful treatment of the structural lesion.

There is no evidence that any pathology of the ear can cause headache without concomitant otalgia. Structural lesions of the pinna, external auditory canal, tympanic membrane, or middle ear may give rise to primary otalgia associated with headache. Headache attributed to disorders of the ear is experienced as ear fullness, throbbing, pressure and tenderness, phonophobia, burning, or itching. The pain can radiate to vertex and temples and can involve half of the head or even the global head. Pain intensity may vary from mild to quite severe. The character is described as dull, aching, or lancinating. Associated symptoms may be tinnitus, hearing loss, or vertigo. Pathologic changes are often visible by examination, and manipulation may increase the pain intensity. Retroauricular or subauricular lymphadenitis is a common accompaniment that can increase pain and pressure.

Jun 21, 2016 | Posted by in PAIN MEDICINE | Comments Off on Disorder of Ear, Nose, and Sinus

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