The average adult blood volume represents 7% of body weight (or 70 mL/kg of body weight) [2]. Estimated blood volume for a 70 kg person is approximately 5 L.

Yes, maintaining a higher hemoglobin level of 10 g/dL is a reasonable goal in actively bleeding patients and with signs of shock. Hemoglobin concentration in an actively bleeding individual has dubious diagnostic value because it takes time for the various intravascular compartments to equilibrate. Hemoglobin concentration should not be the only therapeutic guide for blood transfusion in actively bleeding patients. Rather, therapy should be guided by the rate of bleeding and changes in hemodynamic parameters.