CHAPTER 69 CLINICAL DIAGNOSIS OF PE

Clinical Features From the History and Physical Examination That Predict the Presence or Absence of Pulmonary Embolism in Symptomatic Emergency Department Patients: Results of a Prospective, Multicenter Study

Courtney DM, Kline JA, Kabrhel C, et al. Ann Emerg Med. 2010;55(4):307–315

BACKGROUND

Pulmonary embolism (PE) is a disease with high mortality that is challenging to diagnose. Several pretest probability models utilize elements of history and physical examination (H&P) in predicting the likelihood of the diagnosis of PE, however, each individual H&P elements had yet to be validated in the ED setting. This study aimed to evaluate the soundness of various commonly used elements of H&P as predictors of diagnosis or exclusion of PE in large ED populations.

OBJECTIVE

To assess individual predictive values of 25 variables commonly used for the diagnosis of PE.

METHODS

Prospective, noninterventional, observational study, across 12 US centers (12 sites, nine teaching, and three community practices), between 2003 and 2006.

Participants

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