Anticholinergics



Anticholinergics





Anticholinergic intoxication can occur with a wide variety of prescription and over-the-counter medications and with numerous plants and mushrooms. Common drugs that have anticholinergic activity include antihistamines (See Antihistamines), antipsychotics (See Antipsychotic Drugs, Including Phenothiazines), antispasmodics, skeletal muscle relaxants (See Skeletal Muscle Relaxants), and tricyclic antidepressants (See Antidepressants, Tricyclic). Common combination products containing anticholinergic drugs include Atrohist, Donnagel, Donnatal, Hyland’s Teething Tablets, Lomotil, Motofen, Ru-Tuss, Urised, and Urispas. Common anticholinergic medications are described in Table II–5. Plants and mushrooms containing anticholinergic alkaloids include jimsonweed (Datura stramonium), deadly nightshade (Atropa belladonna), and fly agaric (Amanita muscaria).







Table II-5 Anticholinergic Drugsa