Anesthesia in Resource-Poor Settings: The Médecins Sans Frontières Experience

Country
Project
Context
Program description
Afghanistan
Kabul
Conflict
Obstetrics, general surgery
Khost
Conflict
Obstetrics
Kunduz
Conflict
Obstetrics, general surgery
Burundi
Gitega
Post-conflict
Obstetrics (fistula repair)
Kabezi
Post-conflict
Obstetrics
DRC
Masisi
Conflict
Obstetrics, general surgery
Niangara
Conflict
Obstetrics, general surgery
Haiti
Tabarre
Stable
Orthopaedics, general surgery
India
Mon
Stable
Obstetrics, general surgery
Mali
Douentza
Conflict
Obstetrics, general surgery
Mauritania
Bassikounou
Conflict
Obstetrics, general surgery
Pakistan
Timurgara
Conflict
Obstetrics, general surgery
Philippines
Guiuan
Natural disaster
Obstetrics, general surgery
Sierra Leone
Bo
Post-conflict
Obstetrics
South Sudan
Gogrial
Conflict
Obstetrics, general surgery
Gumuruk
Conflict
General surgery
Somalia
Burao
Conflict
Obstetrics, general surgery
Syria
Jabal-Akkrad
Conflict
Obstetrics, general surgery
The core activity at these projects is the provision of lifesaving and essential surgery that requires only low technology and is based in district hospitals or in the subset of primary health centers with surgical capacity. Lifesaving surgery is defined as any procedure performed in response to an acute state in which the patient’s life, organ, or limb is at stake and surgery must be done as soon as possible, usually within hours. Essential surgery addresses conditions that may not immediately affect health or life but will considerably impair the quality of life or present a serious future health threat, and that are amenable to a proven surgical treatment.
Table 9.2 gives an overview of the main surgical activities in these and 10 other (no longer active) surgery projects during the years 2010–2013 [7]. Focusing on the 14,199 patients treated in 2013, the most common indication for surgery was obstetrical (44.6 % of all patients), 79 % of which were Caesarean sections (data not shown). Accidental trauma was second (26.8 %), followed by violent trauma (10.2 %). At the same time, certain projects involved more complex, specialized types of surgery, for example, high-standard orthopedic procedures such as osteosynthesis and obstetric fistula repair.
Table 9.2
Overview of surgical activities, 2010–2013
Indicator (#)
Total
2013
2012
2011
2010
Patientsa
59,824
14,199
14,583
19,296
11,746
Casesb
77,048
19,395
19,145
22,964
15,544
Proceduresc
83,004
21,774
20,865
24,101
16,264
Main surgical indicators
Violent traumad
4,767 (xx %)
1,445 (10.2 %)
1,277 (8.8 %)
1,086 (5.6 %)
959 (8.2 %)
Accidental trauma
10,283 (xx %)
3,808 (26.8 %)
3,075 (21.1 %)
1,927 (12 %)
1,473 (12.5 %)
Obstetricale
25,719 (xx %)
6,337 (44.6 %)
6,785 (46.5 %)
7,644 (47.5 %)
4,953 (42.2 %)
Other pathologies
15,876 (xx %)
2,609 (18.4 %)
3,446 (23.6 %)
5,460 (34.0 %)
4,361 (37.1 %)
Total
56,605
14,199
14,583
16,077
11,746
CK 56,646
No. of projectsf
 
18
22
21
19
aNumber of new cases
bNumber of Operating Room. visits
cNumber of surgical procedures performed during an intervention. MSF data tools allow reporting up to three procedures. For data analysis, only the first entry is considered because not all projects reported multiple procedures in one surgical intervention
dViolent trauma cases as cause for intervention (only new cases)
ePercentage of Caesarean sections uses patient number (new cases) as the denominator
fNumber of active projects during 2013
In terms of anesthesia practice, around 90 % of all surgeries in 2010–2013 used either general or spinal anesthesia, as shown in Table 9.3. General anesthesia in most MSF contexts uses the intravenous agents ketamine and thiopental as well as the inhalation agent halothane. We consider ketamine an excellent choice for field settings due to its ease of use and safety profile and its widespread uptake throughout middle- and low-income countries (Table 9.4). (However, projects that use ketamine must have resuscitation material available, due to the known risk of respiratory arrest.) Drugs used for muscular relaxation and intubation include depolarizing agents (suxamethonium) and non-depolarizing agents (vecuronium, atracurium).
Table 9.3
Types of anesthesia used at surgical projects, 2013
Type of anesthesia
2013
2012
2011
2010
#
%
#
%
#
%
#
%
Spinal
7,208
37.2
7,294
38.1
7,797
39.7
5,224
33.6
General
7,945
41.0
7,971
41.6
7,961
40.5
7,033
45.2
Intubated
2,183
11.2
1,933
10.1
2,110
10.7
1,636
10.5
Local/regional
1,417
7.3
1,383
7.2
1,191
6.1
1,139
7.4
Combined/others
642
3.3
564
3.0
585
3.0
512
3.3
Total
19,395
100.0
19,145
100.0
19,644
100.0
15,544
100.0
Table 9.4
Ketamine doses and administration at MSF-Belgium surgical projects
Parameter
Anesthesia
Analgesia
Route
IM/rectal
IV
IM
IV
Dose (mg/kg)
8–10
1–2
2–4
0.3–0.8
Onset (min)
5
1–2
5
1–2
Duration (min)
20–30
10–15
Maintenance (mg/kg)
5
0.5–1
Frequency (min)
20–30
15–20
Spinal anesthesia (SA) is indicated for surgery below the umbilicus, i.e., lower limb surgery, surgery of the inguinal area and amputations; for Caesarean sections we use hyperbaric bupivacaine. Neither adrenaline nor opioids are added to our protocols, as we see no clear advantage.

Principles in MSF Field Anesthesia Practice

A key first principle in our surgical missions is that it is feasible, although challenging, to do safe anesthesia with basic tools and infrastructure: after all, millions of episodes of anesthetic administration are performed safely around the world every year in relatively low-technology settings. Clearly this requires anaesthetists with certain critical skills, but a trained anesthesiologist should know how to deal with the types of emergency situations (such as hemorrhagic shock or polytrauma), which happen everywhere. So in this sense there should be no essential difference between anesthetic practices in Western versus resource-poor settings; the difference is in practical implementation stemming from context-specific constraints.

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Oct 18, 2016 | Posted by in ANESTHESIA | Comments Off on Anesthesia in Resource-Poor Settings: The Médecins Sans Frontières Experience

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