The anatomy of pelvic pain can conveniently be divided into the clinical anatomy and biomechanics of the pelvis (see Chapter 2.2) and the anatomy of the pelvic floor (Chapter 2.3). However, the human body operates as a system (Ahn et al. 2006, Reeves et al. 2007) and cannot be divided quite so simplistically. Each component of the movement system is likely to influence distal and proximal regions, it is modulated by many factors from across somatic, psychological and social domains (Moseley 2007, Fall et al. 2010) and ultimately it is controlled by the central nervous system (CNS). It is therefore important always to remind ourselves not to focus solely on the end organ that we may perceive to be ‘at fault’, particularly as the relationship between pain and the state of the tissues becomes weaker as pain persists (Moseley 2007).