Studies of Outcomes, Risks, Costs, and Benefits

Dietary ω-3 fatty acid and fish intake and incident age-related macular degeneration in women

Christen WG, Schaumberg DA, Glynn RJ, et al (Brigham and Women’s Hosp and Harvard Med School, Boston, MA) Arch Ophthalmol 129:921-929, 2011^§

Abstract

Objective

To examine whether intake of ω-3 fatty acids and fish affects incidence of age-related macular degeneration (AMD) in women.

Design

A detailed food-frequency questionnaire was administered at baseline among 39 876 female health professionals (mean [SD] age: 54.6 [7.0] years). A total of 38 022 women completed the questionnaire and were free of a diagnosis of AMD. The main outcome measure was incident AMD responsible for a reduction in best-corrected visual acuity to 20/30 or worse based on self-report confirmed by medical record review.

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